|
|
(13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine <=> 3-O-acetyl-4''-O-demethylpapaveroxine + H+
|
not assigned
|
–
|
| |
KEGG:
R11691
MetaCyc:
RXN-13809
|
|
|
|
narcotine_hemiacetal + NAD+ <=> noscapine + NADH + H+
|
1.1.1.415
noscapine synthase
|
–
|
| |
BRENDA:
BR52506
KEGG:
R10020
MetaCyc:
RXN-13812
|
|
|
|
S-adenosyl-L-methionine + 3-O-acetyl-4''-O-demethylpapaveroxine <=> 3-O-acetylpapaveroxine + S-adenosyl-L-homocysteine + H+
|
2.1.1.352
3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase
|
–
|
| |
BRENDA:
BR52574
KEGG:
R11692
MetaCyc:
RXN-13810
|
|
|
|
O2 + (S)-reticuline <=> H+ + H2O2 + (S)-scoulerine
|
1.21.3.3
reticuline oxidase
|
–
|
| |
BRENDA:
BR36965
KEGG:
R03831
MetaCyc:
RETICULINE-OXIDASE-RXN
|
|
|
|
S-adenosyl-L-methionine + (S)-canadine <=> (S)-N-methylcanadine + S-adenosyl-L-homocysteine
|
2.1.1.122
(S)-tetrahydroprotoberberine N-methyltransferase
|
–
|
| |
KEGG:
R08789
MetaCyc:
RXN-13806
|
|
|
|
S-adenosyl-L-methionine + (S)-scoulerine <=> H+ + S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine
|
2.1.1.117
(S)-scoulerine 9-O-methyltransferase
|
–
|
| |
BRENDA:
BR1438
KEGG:
R03835
MetaCyc:
2.1.1.117-RXN
SABIO-RK:
3591
|
|
|
|
(S)-N-methylcanadine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-1-hydroxy-N-methylcanadine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.166
(S)-N-methylcanadine 1-hydroxylase
|
–
|
| |
MetaCyc:
RXN-13807
|
|
|
|
(S)-1-hydroxy-N-methylcanadine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (13S,14R)-1,13-dihydroxy-N-methylcanadine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.163
(S)-1-hydroxy-N-methylcanadine 13-hydroxylase
|
–
|
| |
MetaCyc:
RXN-19906
|
|
|
|
3-O-acetylpapaveroxine + H2O <=> narcotine_hemiacetal + acetate + H+
|
3.1.1.105
3-O-acetylpapaveroxine carboxylesterase
|
–
|
| |
BRENDA:
BR52695
KEGG:
R12347
MetaCyc:
RXN-13811
|
|
|
|
(S)-tetrahydrocolumbamine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-canadine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.68
(S)-canadine synthase
|
–
|
| |
MetaCyc:
1.1.3.36-RXN
|
|
|
|
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.167
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase
|
–
|
| |
MetaCyc:
RXN-13808
|
|
|
|
acetyl-CoA + (13S,14R)-1,13-dihydroxy-N-methylcanadine <=> (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA
|
2.3.1.285
(13S,14R)-1,13-dihydroxy-N-methylcanadine 13-O-acetyltransferase
|
–
|
| |
BRENDA:
BR52689
KEGG:
R11689
MetaCyc:
RXN-19905
|
|
